Product Description
FASTest C. perfringens
The gram positive anaerobic bacterium Clostridium perfringens belongs to the physiological intestinal fl ora of many mammals and is facultative pathogenic. Inconvenient endogeneous (other basic diseases, diarrhoea pathogens, antibiotic therapies with massive reduction of intestinal fl ora etc.) and exogeneous (farming conditions, extreme changes of the food, stress etc.) factors can lead to an increased pathogenicity of C. perfringens.
Next to its ability to form extremely infectious and stable spores, the formation of lethal toxins is crucial for its pathogenicity. The classifi cation into the various types (A–E) is only due to the toxin formation. These toxins can cause extremely variable (mild to lethal progression forms) failures of the intestinal water and electrolyte balance in the different species like goat, sheep (e. g. dysenteria of lambs: type B; pulpy kidney disease: type D), cattle (haemorrhagic enteritis: type A–E), foal (haemorrhagic necrotising enteritis: type A & C) and piglet (e. g. serous-catarrhal enteritis: type A, necrotising enteritis: type C). Main symptom is extreme and therapy resistant diarrhoea with liquid-stinking feces with blood, later fi brin additions. Often, only an infl ated abdomen can be present in acute cases. Because an antibiotic treatment without aetiological detection is con-traindicated, a fast and safe diagnostics is mandatory.
By its high sensitivity and specifi city, the use of FASTest® C. perfringens allows the veterinarian a rapid aetiological on-site diagnosis of a C. perfringens infection, the quick initiation of therapy as well as of necessary quarantine and prophylaxis measures.
